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Matlab was an paschimfatehpur Upazila (subdistrict) of Chandpur District in the Division of Chittagong, Bangladesh.[1] In 2000, the administrative area was subdivided into Matlab Dakshin Upazila and Matlab Uttar Upazila.[1] Matlab Health and Demographic Surveillance Site (HDSS) was established in 1963 by the Pakistan-SEATO Cholera Research Laboratory (PSCRL). The Matlab population is the largest population under continuous surveillance in the world. The area is typical to many many rural and riverine deltas of Bangladesh. Matlab, a rural area, about 50 km south of Dhaka is one of the richest and longest running longitudinal data source of developing world.[2] In 1960, a group of American and Bangladeshi scientists started drifting around a cholera-prone sub-district of Bangladesh boarded on a barge turned floating cholera hospital. The barge used to float around Matlab with scientists and doctors to treat the patients with cholera from remote places. This is the commencing story of Matlab HDSS which would develop into the Matlab Health Research Centre- a full-fledged health care facility and one of the most important research sites in the world.